Skip to content
Op. Dr. Mustafa AkyüzOrthopedics and Traumatology
Regenerative medicine — preparing a biological treatment in a laboratory setting

Stem Cell and Regenerative Treatments

Regenerative medicine aims to reduce pain and improve function in cartilage damage and osteoarthritis by harnessing the body's own capacity for repair.

Book an Appointment for This Treatment

Regenerative treatments are biological methods that aim to support the repair of damaged tissue by harnessing the body's own healing capacity. In orthopedics, they are used particularly in early- and mid-stage osteoarthritis, cartilage damage, and chronic tendon problems, with the goal of delaying or avoiding joint replacement surgery.

Main Regenerative Methods

PRP (Platelet-Rich Plasma)

PRP involves injecting plasma rich in growth factors, obtained from the patient's own blood, into the affected joint or tendon. Because of its healing-stimulating effect, it is preferred especially for early-stage osteoarthritis and chronic tendon problems.

Stem Cell Applications

This involves applying stem cell-containing concentrates, obtained from bone marrow or adipose (fat) tissue, to the damaged joint. Through the signaling molecules they release into their environment, stem cells suppress inflammation and support tissue repair. The procedure is generally performed under local anesthesia in a short session.

Other Intra-Articular Injections

Treatments such as hyaluronic acid (joint fluid supplementation) and ozone help control symptoms by improving joint lubrication and reducing inflammation. Which method is appropriate is determined by the stage of the disease and the patient's expectations.

Who Is a Suitable Candidate?

  • Patients with early- or mid-stage knee osteoarthritis
  • Patients who are considered too early for joint replacement or who wish to postpone surgery
  • Active individuals with limited cartilage damage
  • Those with chronic tendon problems (tennis elbow, Achilles tendinitis) who have not responded to standard treatment

Realistic Expectations Matter

Regenerative treatments do not regrow cartilage that has been lost in advanced, bone-on-bone osteoarthritis. The goals are to reduce pain, improve function, and slow the progression of the disease. That is why a thorough evaluation and honest counseling before the procedure are the most important steps of the treatment.

The right method, for the right patient, at the right stage — these are the three keys to success in regenerative treatment.

After the Procedure

Avoiding strenuous activity for a few days after the injection is recommended. The effect generally develops gradually over the following weeks. Treatment delivers the best results when it is planned together with a personalized exercise program and weight management.

Frequently Asked Questions

Does stem cell therapy cure osteoarthritis completely?
No; it does not fully restore cartilage that has been lost. The goals are to reduce pain, improve joint function, and slow progression. The best results are achieved in the early and middle stages.
What is the difference between PRP and stem cell therapy?
PRP uses growth factors obtained from the blood and acts mainly as a stimulant for healing. Stem cell applications, using cells obtained from bone marrow or adipose tissue, provide stronger support for tissue repair. The choice depends on the type and stage of the problem.
Is the procedure painful, and how long does recovery take?
The procedures are performed under local anesthesia, and most patients return to daily life the same day. Mild pain at the injection site may last a few days; a noticeable effect is generally felt within 3-6 weeks.
Can these treatments replace joint replacement surgery?
In advanced osteoarthritis, they do not replace joint replacement surgery; however, in suitable patients they can postpone the need for a prosthesis by years. After your evaluation, the most appropriate option for you is explained clearly.

The information on this page is for general informational purposes only; it does not replace an examination or diagnosis. Treatment decisions can only be made after evaluation by a physician.

Don't Put Off Your Symptoms

Let's find the cause of your pain together. Message us on WhatsApp and we'll schedule your appointment quickly.